Thermo Fisher Scientific H2BK20ac Monoclonal Antibody (GT578)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

GT578

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H2BK20ac (acetyl Lys20). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:H2BK20ac,uniProtId:O60814-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_O60814-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_O60814-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:H2BK20ac,uniProtId:Q93079-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q93079-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q93079-1_House_mouse_PDP.jpeg,sortOrder:10},{targetFamily:H2BK20ac,uniProtId:Q99877-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q99877-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q99877-1_House_mouse_PDP.jpeg,sortOrder:11},{targetFamily:H2BK20ac,uniProtId:Q99879-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q99879-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q99879-1_House_mouse_PDP.jpeg,sortOrder:12},{targetFamily:H2BK20ac,uniProtId:Q99880-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q99880-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q99880-1_House_mouse_PDP.jpeg,sortOrder:13},{targetFamily:H2BK20ac,uniProtId:P57053-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_P57053-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_P57053-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:H2BK20ac,uniProtId:P62807-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_P62807-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_P62807-1_House_mouse_PDP.jpeg,sortOrder:3},{targetFamily:H2BK20ac,uniProtId:P06899-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_P06899-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_P06899-1_House_mouse_PDP.jpeg,sortOrder:4},{targetFamily:H2BK20ac,uniProtId:P23527-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_P23527-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_P23527-1_House_mouse_PDP.jpeg,sortOrder:5},{targetFamily:H2BK20ac,uniProtId:P33778-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_P33778-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_P33778-1_House_mouse_PDP.jpeg,sortOrder:6},{targetFamily:H2BK20ac,uniProtId:Q16778-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q16778-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q16778-1_House_mouse_PDP.jpeg,sortOrder:7},{targetFamily:H2BK20ac,uniProtId:Q5QNW6-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q5QNW6-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q5QNW6-1_House_mouse_PDP.jpeg,sortOrder:8},{targetFamily:H2BK20ac,uniProtId:Q8N257-1,ncbiNodeId:9606,antigenRange:20,antigenLength:126,antigenImageFileName:MA5-31551_H2BK20ac_Q8N257-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31551_H2BK20ac_Q8N257-1_House_mouse_PDP.jpeg,sortOrder:9}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787179

Product Specific Information

Keep as concentrated solution.

Positive Control: HeLa (0.4 uM Trichoststin A treatment for 18 hr).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.