Thermo Fisher Scientific MAP2 Polyclonal Antibody
MAP2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(F), ICC/IF에 사용 가능. Mouse 및 Rat 반응성. 신경세포 구조 연구 및 신경퇴행성 질환 연구에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Mouse MAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792893 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%).
- Positive Control: Mouse brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis.
The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins enriched in dendrites, playing a role in determining and stabilizing dendritic shape during neuron development.
MAP2 is useful in studies of neuron structure in normal and malignant brain tissue, as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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