Thermo Fisher Scientific ErbB2 (HER-2) Chimeric Recombinant Rabbit Monoclonal Antibody (FWP51)
ErbB2(HER2) 단백질을 인식하는 재조합 토끼 단클론 항체입니다. 인간 시료에 반응하며 ICC/IF, Flow Cytometry, IP에 사용 가능합니다. Protein A로 정제된 액상 형태로 제공되며, 1 mg/mL 농도입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FWP51 |
| Immunogen | 20×10⁶ SKBR3 human breast tumour cells were injected into BALB/c mice. The hybridomas generated from the mice spleen cells were then screened for antibodies reactive to c‑erbB‑2 using immunofluorescence and immunoprecipitation. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3074633 |
Product Specific Information
Specificity: FWP51 binds to the extracellular domain of c‑erbB‑2.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2‑positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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