Thermo Fisher Scientific CYP2R1 Polyclonal Antibody
Rabbit polyclonal antibody against human CYP2R1, validated for IHC (paraffin). Antigen affinity purified and supplied in PBS with 40% glycerol. Detects vitamin D hydroxylase enzyme involved in vitamin D metabolism. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CYP2R1. Recombinant protein control fragment (Product # RP-90562) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856577 |
Product Specific Information
Immunogen sequence:
TYEDTDFQHM IELFSENVEL AASASVFLYN AFPWIGILPF GKHQQLFRNA AVVYDFLSRL IEKASVNRKP QLPQHFVDAY LDEMDQGKND PSSTFSKENL IFSVGELIIA GTETTTNVLR
Target Information
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. These proteins are monooxygenases that catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. This enzyme functions as a microsomal vitamin D hydroxylase, converting vitamin D into the active ligand for the vitamin D receptor. Mutations in the CYP2R1 gene are associated with selective 25-hydroxyvitamin D deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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