Thermo Fisher Scientific eIF3b Recombinant Rabbit Monoclonal Antibody (23GB3830)
Recombinant rabbit monoclonal antibody targeting human eIF3b. Validated for WB, ICC/IF, and Flow Cytometry. High specificity and reproducibility using HEK293F expression system. Suitable for research on translation initiation and protein synthesis regu...
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific eIF3b Recombinant Rabbit Monoclonal Antibody (23GB3830)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3830 |
| Immunogen | Synthetic peptide of human eIF3B (151–200 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, essential for multiple steps in protein synthesis initiation. The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S pre-initiation complex (43S PIC). It promotes mRNA recruitment and scanning for AUG recognition, and is required for disassembly and recycling of post-termination ribosomal complexes. Additionally, eIF-3 selectively regulates translation of mRNAs involved in cell proliferation, differentiation, and apoptosis through RNA stem-loop interactions. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 원본은 이 섹션에 배치됩니다)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.