Thermo Fisher Scientific CDH10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 250-394. Recombinant protein control fragment (Product #RP-109975). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDH10,uniProtId:Q9Y6N8-1,ncbiNodeId:9606,antigenRange:250-394,antigenLength:788,antigenImageFileName:PA5-144705_CDH10_Q9Y6N8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144705_CDH10_Q9Y6N8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091929

Product Specific Information

Immunogen sequence: SGTTTVNITL TDVNDNPPRF PQNTIHLRVL ESSPVGTAIG SVKATDADTG KNAEVEYRII DGDGTDMFDI VTEKDTQEGI ITVKKPLDYE SRRLYTLKVE AENTHVDPRF YYLGPFKDTT IVKISIEDVD EPPVFSRSSY LFEVH

Antigen sequence identity: Mouse 97%; Rat 97%

Target Information

CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein`s homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.