Thermo Fisher Scientific Villin (GI-Mucosal and Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody (VIL1/2310R)
GI 및 요로계 브러시 보더 마커로 사용되는 Villin 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot 및 면역조직화학(IHC)에 적합. HEK293 세포에서 발현된 고순도 항체로, Protein A/G로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | VIL1/2310R |
| Immunogen | A recombinant fragment (around aa179–311) of human Villin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Villin is part of the cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border.
It interacts with actin in a Ca²⁺ and phosphoinositide-regulated manner.
Villin serves as a specific marker for adenocarcinomas of the gastrointestinal tract and pancreas, and is also expressed in certain Merkel cell tumors and adenocarcinomas of the lung, prostate, ovary, and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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