Thermo Fisher Scientific PPBP Polyclonal Antibody
Rat 유래 PPBP 단백질을 인식하는 염소 다클론 항체로, WB, IHC, Neutralization에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
| Neutralization (Neu) | 0.8–4.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant rat CXCL7/Thymus Chemokine-1 Ile46–Ile107 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610675 |
Product Specific Information
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a conserved Cys-X-Cys motif and are chemotactic for neutrophils.
The platelet basic protein (PBP), a member of this family, is stored in platelet α-granules and released upon activation. Proteolytic cleavage of PBP generates several peptides, including mature PBP, connective tissue-activating peptide III (CTAP III, also known as LA-PF4), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2).
PBP and its derivatives play roles in inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The human PBP gene is located on chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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