Thermo Fisher Scientific G6PD Polyclonal Antibody
G6PD 단백질을 인식하는 염소 유래 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간에 반응하며 개, 생쥐, 랫드에서도 예측 반응. 0.5 mg/mL 농도의 액상 항체로 TBS buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KPASTNSDDVRDEK) corresponding to the internal amino acids of G6PD (aa 275–289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982046 |
Product Specific Information
- This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, a key electron donor in defense against oxidizing agents and in reductive biosynthetic reactions.
G6PD shows high genetic diversity, with many variants resulting from missense mutations, leading to variable enzyme activity and clinical symptoms.
G6PD deficiency can cause neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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