Thermo Fisher Scientific NR2C2 Monoclonal Antibody (OTI1D6), TrueMAB
NR2C2 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D6). Western blot에 최적화되어 있으며, Human 시료에 반응합니다. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose)로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–241 of human NR2C2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. These proteins contain:
- An N-terminal transactivation domain
- A central DNA-binding domain with two zinc fingers
- A C-terminal ligand-binding domain
The activated receptor/ligand complex translocates to the nucleus and binds to hormone response elements of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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