Thermo Fisher Scientific Claudin 1 Monoclonal Antibody (2H10D10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

View 53 publications 53 publications

Immunohistochemistry (IHC)

-

View 14 publications 14 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

View 7 publications 7 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

5-10 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1-5 µg/mL

View 24 publications 24 publications

Flow Cytometry (Flow)

-

View 1 publication 1 publication

ELISA (ELISA)

0.1-1.0 µg/mL

-

Immunoprecipitation (IP)

10 µg/test

-

Miscellaneous PubMed (Misc)

-

View 16 publications 16 publications

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Published species

Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat, Rhesus monkey

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2H10D10

Immunogen

Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Claudin 1,uniProtId:O95832-1,ncbiNodeId:9606,antigenRange:211,antigenLength:211,antigenImageFileName:37-4900_Claudin_1_O95832-1_House_mouse.svg,antigenImageFileNamePDP:37-4900_Claudin_1_O95832-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Alexa Fluor 488
• Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533323

Product Specific Information

Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates.

This antibody is specific for the C-terminal region of the claudin-1 protein. On western blots, it identifies the target band at ~22 kDa.

Target Information

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.