Thermo Fisher Scientific MAdCAM1 (soluble) Monoclonal Antibody (355G8)
인간 MAdCAM-1의 가용성 형태를 인식하는 mouse monoclonal antibody. Western blot, IHC, ELISA, 기능적 분석에 사용 가능. 고순도 Protein A 정제, PBS buffer에 0.1% sodium azide 포함, -20°C 보관.
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Thermo Fisher Scientific MAdCAM1 (soluble) Monoclonal Antibody (355G8)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | View 2 publications |
| ELISA | Assay-dependent | - |
| Functional Assay | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 355G8 |
| Immunogen | Recombinant soluble form of MAdCAM-1-Fc (first Ig domain) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533327 |
Target Information
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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