Thermo Fisher Scientific SMPD4 Polyclonal Antibody
SMPD4 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. 인간, 마우스, 랫트에 반응하며 IHC(P) 등 다양한 응용 가능. 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C 권장.
- 판매단위
- pk
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Thermo Fisher Scientific SMPD4 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human SMPD4 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.78 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 0.1M glycine, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736636 |
Product Specific Information
- Predicted Reactivity: Human (100%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The SMPD4-encoded protein is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
Usage Restriction
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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