Thermo Fisher Scientific TEF Polyclonal Antibody
TEF 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 항원으로 제작되었으며, 액상 형태로 -20°C 보관. 연구용 전용 시약.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TEF (Accession Q10587), corresponding to amino acid residues R204–R254 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854164 |
Product Specific Information
Antibody detects endogenous levels of total TEF.
Target Information
TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor belonging to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily.
TEF binds DNA as a homodimer or heterodimer and transactivates the TSH beta promoter. It is broadly expressed in adults but localized to the developing embryonic anterior pituitary gland. TEF exhibits circadian rhythmic accumulation and can inhibit cell growth by downregulating cytokine receptor beta chain expression.
Its functional domains are highly homologous to other PAR-bZIP family members, such as albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF), and chicken vitellogenin gene-binding protein (VBP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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