Thermo Fisher Scientific CD56 (NCAM) Monoclonal Antibody (TULY56), Brilliant Violet 711, eBioscience

Thermo Fisher Scientific CD56 (NCAM) Monoclonal Antibody (TULY56), Brilliant Violet 711, eBioscience™

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 5 µL (0.25 µg)/test

Product Specifications

Available Conjugate Formats

• Alexa Fluor 660, 700
• APC, APC-eFluor 780
• Brilliant UV 395, 563, 661, 737, 805
• Brilliant Violet 421, 605, 650, 786
• eFluor 450, 506
• FITC
• NovaFluor Blue 660-120S, Blue 800, Red 700, Red 710, Red 725, Yellow 690, Yellow 810
• PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 436, 600, 645, 702, 780
• Request custom conjugation

Product Specific Information

This TULY56 monoclonal antibody reacts with human CD56 (Neural Cell Adhesion Molecule, NCAM), a highly glycosylated transmembrane molecule expressed by neurons and NK/NKT cells. It mediates homotypic adhesion of neural cells.

• Epitope recognition: TULY56 does not block CMSSB binding, indicating recognition of different epitopes.
• Fixation compatibility: Performs better after fixation/permeabilization than CMSSB.
• Cross-reactivity: Rhesus macaque.
• Application: Validated for flow cytometry (5 µL/test).
• Emission: 713 nm; Laser: Violet (405 nm).

Note: Use Super Bright Complete Staining Buffer (SB-4401-42) or Brilliant Stain Buffer™ (00-4409-75) to minimize non-specific polymer interactions.

Light sensitivity: Protect from light to prevent photo-induced oxidation.
Fixation: Compatible with IC Fixation Buffer (00-8222-49) or 1-step Fix/Lyse Solution (00-5333-54).
Not compatible with methanol-based fixation.

Trademark: BRILLIANT VIOLET™ is a trademark of Becton, Dickinson and Company. Powered by Sirigen™.

Target Information

CD56 (NCAM) is a transmembrane glycoprotein of the immunoglobulin family involved in cell adhesion, migration, axonal growth, and synaptic plasticity. It is expressed on neurons, NK cells, and subsets of T cells. CD56 serves as a neuroendocrine marker with high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Associated diseases include rabies and blastic plasmacytoid dendritic cell neoplasms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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