Thermo Fisher Scientific Plasma Kallikrein Recombinant Rabbit Monoclonal Antibody (9F6)
인체 KLKB1 유래 합성 펩타이드로부터 제작된 Recombinant Rabbit Monoclonal Antibody (Clone 9F6). IHC 및 ELISA에 사용 가능하며, 높은 특이성과 재현성을 제공. 액상 형태로 0.33 mg/mL 농도, PBS/glycerol buffer에 보존. 연구용 전용 시약.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9F6 |
| Immunogen | A synthesized peptide derived from human KLKB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092819 |
Target Information
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation, and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa through cleavage of an internal Arg-Ile bond. Plasma kallikrein consists of a heavy chain and a light chain held together by a disulfide bond. The heavy chain contains four tandem repeats of approximately 90 amino acids, each forming an apple domain, which is essential for surface-dependent pro-coagulant activity. The light chain contains the catalytic domain homologous to the trypsin family of serine proteases. Deficiency of plasma prekallikrein causes prolonged activated partial thromboplastin time in patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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