Thermo Fisher Scientific Plasma Kallikrein Recombinant Rabbit Monoclonal Antibody (9F6)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA549855 | - | Thermo Fisher Scientific MA549855 Plasma Kallikrein Recombinant Rabbit Monoclonal Antibody (9F6) 100 ul pk | 재고문의 | pk | 0원 | - | 0원 |
Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
ELISA (ELISA)
Assay-dependent
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9F6
Immunogen
A synthesized peptide derived from human KLKB1
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3092819
Target Information
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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