Thermo Fisher Scientific EDG8 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human EDG8 (S1PR5) for IHC(P) applications. Antigen affinity purified, supplied in PBS with 0.1% sodium azide. Suitable for research use only; high specificity confirmed by BLAST identity across species.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human S1PR5 / EDG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551538 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla (100%); Marmoset (89%); Mouse, Rat, Hamster, Dog, Bat (83%).
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may occur both intracellularly as a second messenger and extracellularly as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors, while others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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