Thermo Fisher Scientific Myeloperoxidase Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 1 publication 1 publication

Immunohistochemistry (IHC)

-

View 75 publications 75 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200

View 12 publications 12 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

-

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

-

View 6 publications 6 publications

Flow Cytometry (Flow)

-

View 2 publications 2 publications

ELISA (ELISA)

1:1,000

View 9 publications 9 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Affinity Purification (AP)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Ferret, Hamster, Human, Mouse, Rat, Rhesus monkey

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified human granulocytic MPO if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Myeloperoxidase,uniProtId:P05164-1,ncbiNodeId:9606,antigenRange:1-745,antigenLength:745,antigenImageFileName:PA5-16672_Myeloperoxidase_P05164-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16672_Myeloperoxidase_P05164-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

purified

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11006367

Product Specific Information

PA5-16672 targets Myeloperoxidase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.

The PA5-16672 immunogen is purified human granulocytic MPO.

PA5-16672 detects MPO-DNA complexes in purified PMA-induced human neutrophil extracellular traps in ELISA application.

Concentration is not determined for this particular antibody. The final product is manufactured from stock material based upon a dilution ratio. The antibody is still quality tested to ensure expected performance and lot-to-lot consistency.

Target Information

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer`s Disease, Familial, 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.