
Thermo Fisher Scientific Phospho-RSK Pan (Ser221, Ser227, Ser218, Ser232) Recombinant Superclonal Antibody
RSK1~4의 인산화 부위(Ser221, Ser227, Ser218, Ser232)를 인식하는 Recombinant Superclonal™ 항체로, 인간을 비롯해 원숭이, 쥐, 생쥐에서 반응합니다. 폴리클로날의 민감도와 모노클로날의 특이성을 결합한 고재현성 항체입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RSK1/2/3/4 around the phosphorylation site of Ser221/227/218/223 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633010 |
Product Specific Information
This antibody is predicted to react with Monkey, Rat, and Mouse.
Recombinant rabbit Superclonal™ antibodies are composed of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
They recognize multiple epitope sites on the target, providing high detection sensitivity for low-abundance targets.
Each lot contains a precisely defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability found in traditional polyclonal antibody production.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. Product and performance remain unchanged.
Target Information
The p90 ribosomal S6 kinases (RSKs) form a family of serine/threonine kinases positioned at the terminus of the ERK pathway.
In humans, four isoforms (RSK1–4) exist, each containing two catalytically functional kinase domains activated sequentially by phosphorylation.
RSKs regulate gene expression by phosphorylating transcriptional regulators such as c-Fos, estrogen receptor, NFκB/IκBα, and CREB.
Upon ERK activation, RSK translocates to the nucleus, leading to phosphorylation and activation of transcription factors.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일명: 711336_RSK_Pan_Q15349-1_Rabbit.svg, 711336_RSK_Pan_Q15349-1_Rabbit_PDP.jpeg, 711336_RSK_Pan_Q9UK32-1_Rabbit.svg, 711336_RSK_Pan_Q9UK32-1_Rabbit_PDP.jpeg, 711336_RSK_Pan_Q15418-1_Rabbit.svg, 711336_RSK_Pan_Q15418-1_Rabbit_PDP.jpeg, 711336_RSK_Pan_P51812-1_Rabbit.svg, 711336_RSK_Pan_P51812-1_Rabbit_PDP.jpeg)
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