Thermo Fisher Scientific Phospho-CAD (Ser1859) Polyclonal Antibody
CAD 단백질의 Ser1859 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin) 분석에 적합. 고순도 액상 형태로 제공되며 1 mg/mL 농도. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5105158
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-CAD (Ser1859) Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAD (Accession P27708), corresponding to amino acid residues around phosphorylated Ser1859 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816631 |
Product Specific Information
Antibody detects endogenous levels of CAD only when phosphorylated at Ser1859.
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate.
This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase.
This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 페이지의 항원 구조 이미지 및 제품 관련 시각 자료를 여기에 배치)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.