Thermo Fisher Scientific Phospho-OPRM1 (Ser377) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human OPRM1(Accession P35372), corresponding to amino acid residues around phosphorylated Ser377. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OPRM1,uniProtId:P35372-1,ncbiNodeId:9606,antigenRange:377,antigenLength:400,antigenImageFileName:PA5-105163_OPRM1_P35372-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105163_OPRM1_P35372-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816636

Product Specific Information

Antibody detects endogenous levels of OPRM1 only when phosphorylated at Ser377, which site historically referenced as Ser375.

Target Information

The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.