Thermo Fisher Scientific Phospho-OPRM1 (Ser377) Polyclonal Antibody
OPRM1 단백질의 Ser377 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 인산화된 형태의 OPRM1만 검출. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OPRM1 (Accession P35372), corresponding to amino acid residues around phosphorylated Ser377. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816636 |
Product Specific Information
This antibody detects endogenous levels of OPRM1 only when phosphorylated at Ser377, which site has been historically referenced as Ser375.
Target Information
The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for commonly used opioids such as morphine, heroin, fentanyl, and methadone. It also serves as the main receptor for endogenous opioid peptides including beta-endorphin and enkephalins. The OPRM1 receptor is a member of the G protein-coupled receptor (GPCR) family. There are at least three types of opioid receptors—mu, kappa, and delta—each with distinct pharmacologic profiles.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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