Thermo Fisher Scientific PAR1 Polyclonal Antibody
Rabbit polyclonal antibody against human PAR1 (Thrombin receptor). Validated for WB and IHC applications. Supplied as a liquid, unconjugated form at 1 mg/mL concentration. Recommended positive controls include Jurkat, HUVEC, and unboiled K562 cells.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–90 of Human Thrombin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548064 |
Product Specific Information
- Recommended positive controls: Jurkat, HUVEC, unboiled K562
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
Thrombin is a serine protease involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors, including PAR-1, PAR-2, and PAR-3.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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