Thermo Fisher Scientific PLSCR1 Polyclonal Antibody
PLSCR1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간·생쥐·랫트 반응성. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 세포막 인지질 스크램블링 연구에 활용 가능.
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Thermo Fisher Scientific PLSCR1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human PLSCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719361 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Phospholipid scramblase 1 (PLSCR1) is a calcium-dependent plasma membrane protein that mediates transbilayer movement of phosphatidylserine and other phospholipids upon cytosolic calcium influx. This process contributes to membrane remodeling and phosphatidylserine exposure in apoptotic or injured cells, leading to cell death. PLSCR1 expression is induced by interferons and cytokines, suggesting a role in cytokine signaling. EGF stimulation causes tyrosine phosphorylation of PLSCR1 (Tyr69, Tyr74), enabling interaction with Shc and linking Src kinase activation to EGF receptor signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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