
ELK Biotechnology OBCAM rabbit pAb
인간 OBCAM 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 세포막에 위치한 단백질 검출에 사용되며, 높은 특이성과 재현성을 제공합니다. -20°C에서 1년간 보관 가능합니다.
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OBCAM rabbit pAb
제품 개요
OBCAM rabbit pAb는 인간 OBCAM 단백질을 인식하는 토끼 폴리클로날 항체입니다. IgLON 단백질 초가족에 속하는 OBCAM은 세포막에 위치하며, 오피오이드 수용체 기능에 보조적 역할을 하는 것으로 알려져 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | OBCAM rabbit pAb |
| Alternative Names | OPCML; IGLON1; OBCAM; Opioid-binding protein/cell adhesion molecule; Opioid-binding cell adhesion molecule; IgLON family member 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human OBCAM (AA range: 152-201) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 58 kD |
| Gene ID (Human) | 4978 |
| Human Swiss-Prot No. | Q14982 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded preprotein is proteolytically processed to generate the mature protein localized in the plasma membrane and may have an accessory role in opioid receptor function. The gene has orthologs in rat and bovine. The rat homolog binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands, and acts as a GPI-anchored protein. Due to its high conservation among species, it may play a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one encoding a proteolytically processed isoform. [RefSeq, Jan 2016]
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