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ELK Biotechnology Sin3B rabbit pAb
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ELK Biotechnology Sin3B rabbit pAb

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Sin3B 단백질을 인식하는 토끼 폴리클로날 항체로, WB, ELISA, IHC에 사용 가능. 인간 유래 합성 펩타이드로 면역화. 핵 내 전사 억제 관련 단백질 검출에 적합. -20°C에서 1년 보관 가능.

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pk
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ELK Biotechnology ES2858-100UL Sin3B rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES2858-50UL Sin3B rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Sin3B rabbit pAb

제품명

Sin3B rabbit pAb

제품 정보

항목 내용
Alternative Names SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b
Applications WB; ELISA; IHC
Recommended Dilutions WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000
Immunogen The antiserum was produced against synthesized peptide derived from human SIN3B (AA range: 221–270).
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 130 kDa
Gene ID (Human) 23309
Human Swiss-Prot No. O75182
Cellular Localization Nucleus
Species Reactivity Human; Rat; Mouse

Background

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC-responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD, forming a complex that represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 to repress transcription. Contains 3 PAH (paired amphipathic helix) repeats. Interacts with FOXK1/MNF, MXI, MAD, NCOR1, and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Also interacts with MAD3, MAD4, MAEL, REST, SETDB1 (by similarity), and HCFC1.

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