ELK Biotechnology Matriptase rabbit pAb
인간 ST14 유래 펩타이드로부터 제작된 Rabbit Polyclonal Antibody로, WB, IF, ELISA에 적합합니다. 세포막 단일 통과형 단백질 Matriptase 검출에 사용되며, 암 관련 단백질 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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Matriptase rabbit pAb
공급업체: ELK Biotechnology
제품 개요
Matriptase rabbit pAb는 인간 ST14 유래 합성 펩타이드(AA 10–59)에 대해 생산된 Rabbit Polyclonal Antibody입니다. 이 항체는 암 침윤 및 전이 관련 단백질 연구에 사용되며, Western blot, Immunofluorescence, ELISA 등 다양한 응용에 적합합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product Name | Matriptase rabbit pAb |
| Alternative Names | ST14; PRSS14; SNC19; TADG15; Suppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human ST14 (AA range: 10–59) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 95 kD |
| Gene ID (Human) | 6768 |
| Human Swiss-Prot No. | Q9Y5Y6 |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. It forms a complex with the Kunitz-type serine protease inhibitor HAI-1 and is activated by sphingosine 1-phosphate. Matriptase cleaves and activates hepatocyte growth factor/scattering factor and urokinase plasminogen activator, functioning as an epithelial membrane activator for other proteases and latent growth factors. Its expression has been associated with breast, colon, prostate, and ovarian tumors, implicating its role in cancer invasion and metastasis. (RefSeq, Jul 2008)
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