ELK Biotechnology KV1.5 rabbit pAb
KCNA5 단백질을 인식하는 rabbit polyclonal antibody로, WB, ELISA, IHC에 적합. 인간, 마우스, 랫트에서 반응하며 세포막 단백질 검출에 유용. 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능.
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KV1.5 rabbit pAb
제품 개요
ELK Biotechnology의 KV1.5 rabbit polyclonal antibody는 인간 KCNA5 단백질을 인식하며, 세포막에 위치한 전압 개폐성 칼륨 채널의 연구에 적합한 항체입니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | KV1.5 rabbit pAb |
| Alternative Names | KCNA5; Potassium voltage-gated channel subfamily A member 5; HPCN1; Voltage-gated potassium channel HK2; Voltage-gated potassium channel subunit Kv1.5 |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human KCNA5 (AA range: 253–302) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 68 kDa |
| GeneID (Human) | 3741 |
| Human Swiss-Prot No | P22460 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse roles include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, each with human homologs. The KCNA5 gene encodes a member of the voltage-gated, shaker-related potassium channel subfamily. This protein includes six transmembrane domains with a shaker-type repeat in the fourth segment and belongs to the delayed rectifier class, contributing to the restoration of resting membrane potential after depolarization.
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