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ELK Biotechnology Ku-70 rabbit pAb
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ELK Biotechnology Ku-70 rabbit pAb

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Ku-70 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 인간 Ku70 유래 펩타이드로부터 제작되었으며, 핵 내 Ku 복합체 연구 및 DNA 손상 복구 메커니즘 분석에 유용합니다. -20°C에서 1년 보관 가능합니다.

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pk
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ELK Biotechnology ES2681-100UL Ku-70 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES2681-50UL Ku-70 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Ku-70 rabbit pAb

ELK Biotechnology Ku-70 rabbit pAb

제품 정보

항목 내용
Product name Ku-70 rabbit pAb
Alternative Names XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 1
Applications WB; IHC; IF; ELISA
Recommended Dilutions WB: 1/500–1/2000
IHC: 1/100–1/300
IF: 1/200–1/1000
ELISA: 1/10000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human Ku70 (AA range: 560–609)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 70 kDa
GeneID (Human) 2547
Human Swiss-Prot No. P12956
Cellular Localization Nucleus; Chromosome
Species Reactivity Human; Mouse; Rat

Background

The p70/p80 autoantigen is a nuclear complex composed of two subunits with molecular masses of approximately 70 and 80 kDa. This complex functions as a single-stranded DNA-dependent, ATP-dependent helicase and is involved in the repair of nonhomologous DNA ends, such as those required for double-strand break repair, transposition, and V(D)J recombination. Elevated levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [RefSeq, Jul 2008]

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