ELK Biotechnology KIR6.2 rabbit pAb
KIR6.2 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 막단백질 연구 및 당뇨병 관련 연구에 적합. -20℃ 보관, 1 mg/ml 농도.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology KIR6.2 rabbit pAb
제품명
KIR6.2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | KCNJ11; ATP-sensitive inward rectifier potassium channel 11; IKATP; Inward rectifier K(+) channel Kir6.2; Potassium channel; inwardly rectifying subfamily J member 11 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Kir6.2 (AA range: 190-239) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 3767 |
| Human Swiss-Prot No. | Q14654 |
| Cellular Localization | Membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It allows potassium to flow preferentially into cells and is controlled by G-proteins, associating with the sulfonylurea receptor SUR.
Mutations in this gene cause familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), characterized by unregulated insulin secretion. Defects may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcripts exist.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.