Thermo Fisher Scientific MVK Polyclonal Antibody
Rabbit polyclonal antibody against human MVK, validated for WB, IHC, and ICC/IF. Affinity-purified with >95% purity. Suitable for research on mevalonate kinase function and related metabolic disorders. Supplied as liquid, unconjugated form, 1 mg/mL con...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 150–200 of Human MVK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719016 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by epitope-specific affinity chromatography. Purity is >95% as determined by SDS-PAGE.
Target Information
Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. It catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. MVK deficiency contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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