Thermo Fisher Scientific PFKP Polyclonal Antibody
Rabbit polyclonal antibody targeting human PFKP amino acids 350–400. Validated for IHC(P) and ICC/IF applications. High purity (>95%) and affinity-purified. Supplied as liquid, unconjugated form at 1 mg/mL concentration.
- 카탈로그번호
- PA575287
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 350–400 of Human PFKP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719015 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. The family is classified into 8 major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group includes 63 kinases, such as:
- Cyclic nucleotide-regulated protein kinases (PKA & PKG)
- Diacylglycerol-activated/phospholipid-dependent protein kinases (PKC)
- RAC/Akt protein kinase family
- Kinases that phosphorylate G protein-coupled receptors (ARK)
- Kinases that phosphorylate ribosomal protein S6 (RSK)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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