
Thermo Fisher Scientific NMT2 Polyclonal Antibody
Thermo Fisher Scientific의 NMT2 Polyclonal Antibody는 인간 NMT2 단백질을 인식하는 Rabbit IgG 기반 항체로, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관됩니다.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | 1:200–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Glycylpeptide N-tetradecanoyltransferase 2 protein (1–120AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.29 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091545 |
Target Information
Proteolytic degradation is critical to maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, and signaling. The ubiquitin-proteasome pathway deconstructs most cytosolic and nuclear proteins, while others are degraded via the vacuolar pathway involving endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome, an ATP-dependent multisubunit complex (~2.5 MDa), consists of a 20S core and 19S regulatory subunits that recognize ubiquitinated proteins, unfold them, and translocate them for degradation. Defects in this pathway are linked to several genetic diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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