Thermo Fisher Scientific DDX1 Polyclonal Antibody
Rabbit 유래 다클론 항체로 DDX1 단백질 검출에 사용. Western blot, IHC, IP 등 다양한 응용에 적합. 인간 DDX1의 500–550번 잔기 영역을 면역원으로 사용. 액상 형태, 4°C 보관, 1년 권장 보관기간. 마우스, 랫, 소, 오랑우탄과 교차 반응 예측.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DDX1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | |
| Immunohistochemistry (IHC) | 1:100–1:500 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 500 and 550 of human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, and Orangutan
Target Information
DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase capable of unwinding both RNA-RNA and RNA-DNA duplexes.
It possesses 5′ single-stranded RNA overhang nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides.
DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation and serves as a positive regulator of cyclin CCND2 expression by binding to its promoter region.
It is a component of a multi-helicase-TICAM1 complex that functions as a cytoplasmic sensor of viral double-stranded RNA and plays a role in antiviral response activation, including induction of proinflammatory cytokines via TICAM1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.