Thermo Fisher Scientific AANAT Monoclonal Antibody (OTI3B9), TrueMAB
AANAT 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI3B9). Western blot에 최적화되어 있으며, Human 시료에 반응. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로 melatonin 합성 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–72 of human AANAT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Arylalkylamine N-Acetyltransferase (AANAT) is a key enzyme in melatonin synthesis. Melatonin regulates sleep and circadian rhythm. Fluctuations in AANAT abundance contribute to day/night variations in melatonin levels in the pineal gland and retina. AANAT activity is mainly regulated by protein level control, though recent studies suggest additional mechanisms may influence melatonin production independently of AANAT protein concentration, explaining the rapid nighttime rise in circulating melatonin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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