Thermo Fisher Scientific RAB3GAP1 Polyclonal Antibody
RAB3GAP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(paraffin) 응용에 적합하며, 인간·마우스·랫트 반응성. 고순도(>95%) 항원 친화 크로마토그래피로 정제된 액상 형태.
- 카탈로그번호
- PA537026
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 580–625 of human RAB3GAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553872 |
Product Specific Information
This antibody detects endogenous RAB3GAP1 protein at a molecular weight of 111 kDa.
Purity is >95% by SDS-PAGE.
Target Information
RAB3GAP1 is a 981 amino acid protein belonging to the Rab3-GAP catalytic subunit family. Rab3-GAP p130 converts active RAB3-GTP to the inactive RAB3-GDP form and is essential for normal eye and brain development.
Defects in Rab3-GAP p130 cause Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system, and microgenitalia.
RAB3GAP1 may be involved in neurodevelopmental processes such as proliferation, migration, differentiation before synapse formation, and non-synaptic vesicular neurotransmitter release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-37026_RAB3GAP1_Q15042-1_Rabbit.svg, PA5-37026_RAB3GAP1_Q15042-1_Rabbit_PDP.jpeg)
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