Thermo Fisher Scientific ATP6V1B2 Polyclonal Antibody
ATP6V1B2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 액상 형태로 -20°C에서 보관합니다. 세포 내 막계 및 멜라노솜 단백질 검출에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 262–511 of human ATP6V1B2 (NP_0016842) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2806367 |
Product Specific Information
Immunogen sequence:
NLANDPTIER IITPRLALTT AEFLAYQCEK HVLVILTDMS SYAEALREVS AAREEVPGRR GFPGYMYTDL ATIYERAGRV EGRNGSITQI PILTMPNDDI THPIPDLTGY ITEGQIYVDR QLHNRQIYPP INVLPSLSRL MKSAIGEGMT RKDHADVSNQ LYACYAIGKD VQAMKAVVGE EALTSDDLLY LEFLQKFERN FIAQGPYENR TVFETLDIGW QLLRIFPKEM LKRIPQSTLS EFYPRDSAKH
Positive Samples:
K-562, SW620, 293T, U-251MG, Mouse kidney, Mouse brain, Rat brain
Cellular Location:
Endomembrane system, Melanosome, Peripheral membrane protein
Target Information
ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase-dependent organelle acidification is essential for protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
The V1 domain of V-ATPase contains the ATP catalytic site and is composed of multiple subunits (A, B, G, C, D, E, F, H).
ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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