Thermo Fisher Scientific Bestrophin 2 Polyclonal Antibody
Bestrophin 2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 다양한 종(인간, 마우스 등)에 반응하며 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로 사용.
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- PA533364
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 2.5–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human BEST2 / Bestrophin-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550745 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Bovine, Pig (100%).
Target Information
Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3′ ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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