Thermo Fisher Scientific Bestrophin 3 Polyclonal Antibody
Human BEST3 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 2.5–5 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용되며, BEST3 단백질의 발현 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from internal region of human BEST3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550746 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey: 100%
- Marmoset, Bat: 95%
- Hamster, Elephant, Panda, Bovine, Pig: 90%
- Dog, Rabbit: 85%
Target Information
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (mutant in vitelliform macular dystrophy, VMD), and other BEST1-like genes, BEST2 and BEST4.
Bestrophins are transmembrane (TM) proteins sharing a homology region rich in aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes have a conserved gene structure with nearly identical sizes of the 8 RFP-TM domain-encoding exons and conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3′ end of variable length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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