Thermo Fisher Scientific A2M Monoclonal Antibody (F1-P1C11 #3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

ELISA (ELISA)

2 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

-

Radioimmune Assays (RIA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

F1-P1C11 #3

Immunogen

Purified human plasma AMG if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:A2M,uniProtId:P01023-1,ncbiNodeId:9606,antigenRange:1-1474,antigenLength:1474,antigenImageFileName:MA5-14663_A2M_P01023-1_House_mouse.svg,antigenImageFileNamePDP:MA5-14663_A2M_P01023-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10983307

Product Specific Information

MA5-14663 targets Alpha2-Macroglobulin in ELISA, IP, and RIA applications and shows reactivity with Human samples.

The MA5-14663 immunogen is purified human plasma AMG.

MA5-14663 detects Alpha2-Macroglobulin which has a predicted molecular weight of approximately 162 kDa.

Product MA514663 is a smaller package size of MIA1201 (formerly sold as a Seradyn product).

Target Information

Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer`s disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.