Thermo Fisher Scientific PCGF6 Polyclonal Antibody
Thermo Fisher Scientific의 PCGF6 Polyclonal Antibody는 Human, Mouse, Rat에 반응하며 Western blot에 최적화된 항체입니다. 항원 친화 크로마토그래피로 정제되어 높은 순도를 보장하며, PBS/glycerol 버퍼에서 안정적으로 보관 가능합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA576818
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PCGF6 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PCGF6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720545 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several PcG members contain RING finger domains and are classified as a subclass of RING finger proteins.
The RING-type zinc finger motif is a conserved cysteine-rich domain capable of binding two zinc atoms and is typically involved in the ubiquitination pathway of protein degradation.
PCGF6 (polycomb group ring finger 6), also known as MBLR or RNF134, is a 350 amino acid nuclear protein expressed ubiquitously and contains one RING-type zinc finger. PCGF6 acts as a transcriptional repressor and regulates histone H3K4Me3 levels by activating SmcY histone demethylase. PCGF6 exists as two alternatively spliced isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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