Thermo Fisher Scientific Human RAB21 Synthetic Peptide
인간 RAB21 단백질의 카복시 말단 근처 19개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단 실험용으로 사용 가능. 고순도 정제된 액상 형태로 제공되며, PBS 버퍼(0.1% BSA, 0.02% sodium azide)에 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Human RAB21 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 19 amino acid sequence near the carboxy terminus of human RAB21.
PEP-1446 can be used as a blocking peptide with polyclonal antibody PA5-34404.
Target Information
RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting.
In non-polarized Caco-2 cells, RAB21 shows general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localizes to apical vesicles.
RAB21 associates with integrin subunits and is important for receptor entry into cells via RAB5/RAB21 endosomes.
The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the alpha-tail of endocytosed integrin.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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