Thermo Fisher Scientific Human CRIM1 Synthetic Peptide
Human CRIM1 단백질의 C-말단 부근 17 아미노산 서열을 기반으로 한 합성 펩타이드. PA5-34410 항체의 블로킹 펩타이드로 사용 가능. 인체 조직 발달 및 혈관 형성 연구에 적합. Assay 의존적 희석 사용 권장. 연구용 전용 제품.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid sequence near the carboxy terminus of human CRIM1.
PEP-1452 can be used as a blocking peptide with polyclonal antibody PA5-34410.
Target Information
CRIM1 (cysteine-rich motor neuron 1) is a glycosylated type I transmembrane protein involved in tissue development, such as capillary formation and maintenance during angiogenesis.
It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain.
CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist.
It is developmentally expressed in various tissues including the pancreas, kidney, placenta, brain, and blood vessels.
CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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