Thermo Fisher Scientific Human ZFYVE21 Synthetic Peptide
인간 ZFYVE21 단백질의 N말단 15 아미노산 서열 기반 합성 펩타이드로, PA5-34408 항체의 차단 펩타이드로 사용 가능. Assay 의존적 사용. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 함유. -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to a 15 amino acid sequence near the amino terminus of human ZF21.
PEP-1450 can be used as a blocking peptide with polyclonal antibody PA5-34408.
Target Information
ZF21 was initially identified as a protein that binds to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease.
ZF21 belongs to a protein family characterized by a phosphatidylinositol 3-phosphate-binding FYVE domain and plays a role in regulating focal adhesions (FAs) and cell movement.
Knockdown of ZF21 expression delays FA disassembly following nocodazole-induced synchronous FA disassembly, suggesting ZF21 involvement in this process.
ZF21 also contains a noncanonical pleckstrin homology domain, representing a potential therapeutic target for metastatic cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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