Thermo Fisher Scientific ADSL Recombinant Rabbit Monoclonal Antibody (007)
ADSL 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, ICC/IF, IP에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태입니다. 인간 시료에 반응하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 007 |
| Immunogen | Recombinant Human ADSL (Adenylosuccinate Lyase) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898793 |
Target Information
ADSL (adenylosuccinate lyase), also known as AMPS, ASL, or ASASE, is a 484 amino acid protein involved in purine biosynthesis and the formation of adenosine monophosphate (AMP) from inosine monophosphate. It catalyzes two key reactions in AMP biosynthesis:
- Removal of fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to produce aminoimidazole carboxamide ribotide (AICA).
- Removal of fumarate from adenylosuccinate to yield AMP.
Defects in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder characterized by epilepsy, growth retardation, and muscular wasting. Multiple isoforms exist due to alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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