Thermo Fisher Scientific CD45RC Monoclonal Antibody (3a56), PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1:100

-

Product Specifications

Species Reactivity

Pig

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3a56

Conjugate

PE PE PE

View additional formats

• Unconjugated
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Lyophilized

Purification

Protein A

Storage buffer

PBS with 1% BSA, 5% sucrose

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898790

Product Specific Information

Reconstitute by adding 1 mL distilled water.

Target Information

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.