Thermo Fisher Scientific ACAT2 Monoclonal Antibody (OTI3A8), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene belongs to the frizzled family encoding 7-transmembrane domain proteins that act as receptors for Wnt signaling proteins.
The encoded protein includes a signal peptide, a cysteine-rich N-terminal domain, and seven transmembrane domains but lacks a C-terminal PDZ domain-binding motif.
It functions as a negative regulator of canonical Wnt/β-catenin signaling, thereby inhibiting oncogenic transformation, cell proliferation, and apoptosis inhibition.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.