Thermo Fisher Scientific HSPB8 Monoclonal Antibody (OTI1E3), TrueMAB
HSPB8 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합. 인간 및 랫트 반응성. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 세포 증식, 자가포식 및 신경근 질환 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Full length human recombinant protein of human HSPB8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HSPB8 belongs to the small heat-shock protein superfamily, containing a conserved alpha-crystallin domain at the C-terminal region.
Its expression is induced by estrogen in estrogen receptor-positive breast cancer cells and functions as a chaperone with Bag3 to stimulate macroautophagy.
This gene is involved in cell proliferation, apoptosis, and carcinogenesis, and mutations are linked to neuromuscular diseases such as Charcot-Marie-Tooth disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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