Thermo Fisher Scientific IL4R Monoclonal Antibody (1D3)
인간 IL4R 단백질을 인식하는 마우스 단클론 항체로 ELISA에 적합합니다. 비결합형 액상 형태이며 보존제 없이 -20°C에서 보관합니다. 알레르기 반응 및 Th2 분화 연구에 유용합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00003566-M01A
- 판매단위
- pk
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Applications
- ELISA (ELISA): Tested at 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D3 |
| Immunogen | IL4R (NP_000409, 26 a.a. ~135 a.a) partial recombinant protein with GST tag. MW of GST tag: 26 KDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKVLQEPTCV SDYMSISTCE WKMNGPTNCS TELRLLYQLV FLLSEAHTCI PENNGGAGCV CHLLMDDVVS ADNYTLDLWA GQQLLWKGSF KPSEHVKPRA PGNLTVHTNV
Target Information
IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammation. The IL4 response promotes Th2 differentiation. The secreted extracellular domain of IL4R alpha (sIL4R alpha) can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells, but has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, which can manifest as allergic rhinitis, sinusitis, asthma, or eczema.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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