Thermo Fisher Scientific IL2 Monoclonal Antibody (1C1)

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

ELISA

• Tested Dilution: 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFSQSII STLT

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a critical role in the proliferation of activated T cells and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7.
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression control.
Targeted disruption of an IL-2-like gene in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.