Thermo Fisher Scientific IL3 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSRLPVLLLL QLLVRPGLQA PMTQTTPLKT SWVNCSNMID EIITHLKQPP LPLLDFNNLN GEDQDILMEN NLRRPNLEAF NRAVKSLQNA SAIESILKNL LPCLPLATAA PTRHPIHIKD GDWNEFRRKL TFYLKTLENA QAQQTTLSLA IF

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines.

Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species-specific.
For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth-promoting cytokine capable of supporting proliferation of a broad range of hematopoietic cell types, and is involved in cell growth, differentiation, and apoptosis.
IL-3 also possesses neurotrophic activity and may be associated with neurologic disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.